HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1382003Generated: October 27, 2026
Ethyl 7-chloro-6-fluoro-4-hydroxy-8-nitro-3-quinolinecarboxylate → HCID 178469663, compound
https://huagongshe.com/reaction/1382003
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethyl 7-chloro-6-fluoro-4-hydroxy-8-nitro-3-quinolinecarboxylate | HCID 178469671 | — |
| Catalyst | Iron | HCID 23925 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | HCID 178469663 | HCID 178469663 | — |
Reaction Steps
8.4 g of the product from Example 5 and 19.2 g of iron turnings are warmed at 80° C. for 1 hour in 190 ml of acetic acid. The mixture is then heated briefly to 110° C. and filtered while hot. Ice-water is then added to the filtrate, and the precipitated soid is isolated. After drying at 110° C., the product is recrystallized from glycol monomethyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04804760 |
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| Source dataset | uspto-grants-1989_02 |
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| ORD ID | ord-f4dd66ff24844e7dad3373fbafb9b9b2 |
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| Source note | uspto-grants-1989_02 |
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