HCID 70393482, compound → HCID 70361890, compound

HRID 1382161Notes

Reaction equation

HRID 1382161 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([O:9]C(C)C)=[CH:4][C:3]=1[N:13]1[C:17](=[O:18])[N:16]([CH3:19])[CH:15]([Cl:20])[N:14]1[CH:21]([F:23])[F:22]>S(=O)(=O)(O)O>[Cl:1][C:2]1[CH:7]=[C:6]([Cl:8])[C:5]([OH:9])=[CH:4][C:3]=1[N:13]1[C:17](=[O:18])[N:16]([CH3:19])[CH:15]([Cl:20])[N:14]1[CH:21]([F:23])[F:22]

Participants

3

Reactant 1

HCID 70393482HCID 70393482, compound

Product 1

HCID 70361890HCID 70361890, compoundYield 93.5%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

Hydrolysis of 2.6 g (0.0067 mole) of 1-[2,4-dichloro-5-(1-methylethoxy)phenyl]-3-chlorodifluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one in 10 mL of concentrated sulfuric acid produced 2.17 g of 1-(2,4-dichloro-5-hydroxyphenyl)-3-chlorodifluoromethyl-4,5-dihydro-4-methyl-1,2,4-triazol-5(1H)-one as a solid (mp 146°-148° C.).

Sources & evidence

ORD record
ord-348cb0e9d7e14b6da32d5e95a15258c8
Source dataset
uspto-grants-1989_02
Patent number
US04806145

Reaction notes

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