Benzoyl chloride → HCID 73771260, compound

Participants

Reaction Steps

Aqueous 1% sodium hydroxide solution (6.1 ml) was added to a solution of 2-[1-(ethoxyimino)propyl]-3-hydroxy-5-(2,4,6-trimethoxyphenyl)cyclohex-2-en-1-one (0.52 g; 1.40 mmole) in acetone (25 ml). The mixture was stirred at room temperature for a period of 5 minutes and then benzoyl chloride (0.21 g) was added dropwise. The mixture was stirred for a further period of 15 minutes and then the solvent was removed by evaporation under reduced pressure. The product was purified by chromatography over silica gel (eluant dichloromethane) to give 3-benzoyloxy-2-[1-(ethoxyimino)propyl]-5-(2,4,6-trimethoxyphenyl)cyclohex-2-en-1-one (0.50 g; 73.9%) as a pale yellow solid, mp 139° C.

Provenance & Evidence