HuagongsheHuagongshe Chemistry Print Report · For research reference only
(alphaR,betaR)-N-benzyloxycarbonyl-5-chloro-1-ethyl-beta-methyltryptophan methyl ester → (alphaR,betaR)-5-chloro-1-ethyl-beta-methyltryptophan methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (alphaR,betaR)-N-benzyloxycarbonyl-5-chloro-1-ethyl-beta-methyltryptophan methyl ester | HCID 14152055 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (alphaR,betaR)-5-chloro-1-ethyl-beta-methyltryptophan methyl ester | HCID 14152057 | 85.5% |
Reaction Steps
A solution of (αR,βR)-Nα -Benzyloxycarbonyl-5-chloro-1-ethyl-β-methyltryptophan methyl ester (4.17 g) in methanol (100 ml) containing 10% paradium on charcoal (0.5 g) was hydrogenated. After removal of the catalyst and evaporation of the solvent, (αR,βR)-5-chloro-1-ethyl-β-methyltryptophan methyl ester (2.45 g) was obtained as a yellow amorphous powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806538 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-aa2f9d0ed93b4ba8bfba10d4eb0a218b |
| Source note | uspto-grants-1989_02 |