HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178471921, compound → 3-cyclohexylcarbonyl-8-methoxy-4(1H)-quinolone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178471921 | HCID 178471921 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | 3-cyclohexylcarbonyl-8-methoxy-4(1H)-quinolone | HCID 10016783 | 35.2% |
Reaction Steps
Ethyl 2-cyclohexylcarbonyl-3-(2-methoxyphenylamino)acrylate (20 g, 0.06 mol) was added in portions to boiling diphenyl ether (200 ml) and the mixture was heated under reflux for 1.5 hours. When cool, the mixture was diluted with petroleum ether and allowed to crystallise overnight to give 3-cyclohexylcarbonyl-8-methoxy-4(1H)-quinolone (6.0 g, 35.2%), m.p. 168°-70° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806549 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-21a8ca2d744a4e3a93dc2a7fa5099ca2 |
| Source note | uspto-grants-1989_02 |