HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyaniline → HCID 10246288, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyaniline | HCID 7000 | — |
| Reactant | 3-Butyryl-4-chloro-8-methylquinoline | HCID 10037627 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 10246288 | HCID 10246288 | 33.6% |
Reaction Steps
3-Butyryl-4-chloro-8-methylquinoline (4.95 g, 20mmol), 2-methoxyaniline (4.51 ml, 40mmol) and tetrahydrofuran (20 ml) were stirred at room temperature overnight. The hydrochloride salt was filtered off, converted to free base and recrystallised from ethyl acetate/petroleum ether to give 3-butyryl-4-(2-methoxyphenylamino)-8-methylquinoline (2.25 g), m.p. 135°-137°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806549 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-886a52f8a80c43e383d1b053e72431c9 |
| Source note | uspto-grants-1989_02 |