HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,6-Dimethylaniline → 3-Butyryl-4-(2,6-dimethylphenylamino)-8-methylquinoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,6-Dimethylaniline | HCID 6896 | — |
| Reactant | 3-Butyryl-4-chloro-8-methylquinoline | HCID 10037627 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 3-Butyryl-4-(2,6-dimethylphenylamino)-8-methylquinoline | HCID 10404540 | — |
Reaction Steps
3-Butyryl-4-chloro-8-methylquinoline (2.48 g, 10 mmol) and 2,6-dimethylaniline (1.85 ml, 15 mmol) in dioxan (10 ml) were healed at reflux for 30 minutes, then the solvent evaporated and the product converted to free base. Recrystallisation from aqueous ethanol gave 3-butyryl-4-(2,6-dimethylphenylamino)-8-methylquinoline, m.p. 100°-101°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806549 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-9aad041c5e2e496b982190053a461e00 |
| Source note | uspto-grants-1989_02 |