HuagongsheHuagongshe Chemistry Print Report · For research reference only
O-Toluidine → HCID 10380322, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | O-Toluidine | HCID 7242 | — |
| Reactant | HCID 10466538 | HCID 10466538 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 10380322 | HCID 10380322 | 59.1% |
Reaction Steps
3-Butyryl-4-chloroquinoline (2.33 g, 10 mmol), 2-methylaniline (1.60 ml, 15 mmol) and dioxan (10 ml) were heated at reflux for 30 minutes, then allowed to cool. The hydrochloride salt was filtered off, converted to free base and recrystallised from aqueous ethanol to give 3-butyryl-4-(2-methylphenylamino)quinoline (1.80 g), m.p. 107°-109°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806549 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-b1b0ef08954144e192df30a26f88159d |
| Source note | uspto-grants-1989_02 |