HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 178471922, compound → 3-isobutyryl-8-methoxy-4(1H)-quinolone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 178471922 | HCID 178471922 | — |
| Solvent | Diphenyl Ether | HCID 7583 | — |
| Product | 3-isobutyryl-8-methoxy-4(1H)-quinolone | HCID 10263901 | 52.2% |
Reaction Steps
Ethyl 2-isobutyryl-3-(2-methoxyphenylamino)acrylate (18.8 g, 0.065 mol) was added in portions to boiling diphenyl ether (150 ml). The mixture was heated under reflux for 30 minutes, cooled, and diluted with petroleum ether (500 ml). Filtration of the mixture gave 3-isobutyryl-8-methoxy-4(1H)-quinolone as a light brown solid (8.32 g, 52.2%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806550 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-d3a21179271742f48d65cb7242b33020 |
| Source note | uspto-grants-1989_02 |