HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methoxyaniline → HCID 21274560, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methoxyaniline | HCID 7000 | — |
| Reactant | 3-Butyryl-4-chloro-8-methylquinoline | HCID 10037627 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 21274560 | HCID 21274560 | 86.8% |
Reaction Steps
3-Butyryl-4-chloro-8-methylquinoline (2.33 g, 10 mmol), 2-methoxyaniline (1.69 ml, 15 mmol) and dioxan (10 ml) were heated at reflux for 30 minutes, then allowed to cool. The hydrochloride salt was filtered off, converted to free base and recrystallised from ethanol to give 3-butyryl-4-(2-methoxy-phenylamino)quinoline (2.78 g), m.p. 167°-168°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806550 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-771acb4fded84f84ad1e426c16f5991d |
| Source note | uspto-grants-1989_02 |