Phosphoric Acid → 6-Deoxy-6-(formylamino)-L-sorbose

Participants

Reaction Steps

To a suspension of 40 g of Gluconobacter oxidans spp. suboxidans (DSM 50049) in 1 l of tap water, brought to pH 4.5 with phosphoric acid, are added at 32° C. and 700 rpm with venting of 3 l of air/hour 200 g of N-formylaminosorbitol, followed 4 hours later by a further 200 g of N-formylaminosorbitol. After 22 hours the reaction has ended, the cells are centrifuged off and discarded. The product is isolated as an oil by concentrating in vacuo.

Provenance & Evidence