HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylonitrile → HCID 21274853, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylonitrile | HCID 7855 | — |
| Reactant | 2,6-Dimethylphenol | HCID 11335 | — |
| Reactant | Aluminum(III) Chloride | HCID 6451240 | — |
| Product | HCID 21274853 | HCID 21274853 | — |
Reaction Steps
In a modification of this Friedel-Crafts reaction, 2,6-di-methylphenol is treated with acrylonitrile in the presence of aluminum chloride to yield 3-(3,5-dimethyl-4-hydroxyphenyl)propionitrile. Upon hydrolysis of this and esterification of the resulting free acid with methanol and p-toluenesulfonic acid, there is obtained methyl 3-(3,5-di-methyl-4-hydroxyphenyl)propionate, M.P. 70°-83° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04806675 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-e4109f49f6564814b33164cbbaa2acc3 |
| Source note | uspto-grants-1989_02 |