HCID 22841465, compound → HCID 22841460, compound

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Reaction Steps

A solution of 2-[2-(-(S)-4-benzyloxycarbonylamino-4-carboxybutanamido)ethoxymethyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine (0.97 g) in 10% aqueous ethanol (22 ml) was stirred for 2 hours under an atmosphere of hydrogen [103.4 kPa (15 p.s.i.)] at room temperature in the presence of 5% palladium on carbon (97 mg). The mixture was filtered and evaporated to leave the title compound as an amorphous solid, (0.7 g).

Provenance & Evidence