Chlorine → HCID 21272883, compound

HRID 1382659Notes

Reaction equation

HRID 1382659 reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11]([CH2:14][CH:15]=[CH2:16])=[C:10]([C:17]([F:20])([F:19])[F:18])[NH:9]2)=[CH:4][C:3]=1[Cl:21].[Cl:22]Cl>C(Cl)(Cl)(Cl)Cl>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]2[C:12](=[O:13])[C:11]([CH2:14][CH:15]=[CH2:16])([Cl:22])[C:10]([C:17]([F:18])([F:19])[F:20])=[N:9]2)=[CH:4][C:3]=1[Cl:21]

Participants

4

Reactant 2

HCID 24526ChlorineHCID 21272881HCID 21272881, compound

Product 1

HCID 21272883HCID 21272883, compound

Reagents, catalysts & solvents 1

HCID 5943Carbon TetrachlorideSolvent2×

Conditions

Temperature
0 °C

Procedure

A mixture of 4.06 g of the product of Step A and 150 ml of carbon tetrachloride was cooled to 0° C. and 17.2 ml of chlorine in solution in carbon tetrachloride (1.55 mole per liter) were added. When the reaction was complete, the product was washed with a saturated solution of sodium bicarbonate, with water, dried, treated with active charcoal and stirred for 15 hours, filtered and concentrated to obtain 51 g of 1-(4-bromo-3-chlorophenyl)-3-trifluoromethyl-4-allyl-4-chloro-5-pyrazolone.

Workup

  1. washthe product was washed with a saturated solution of sodium bicarbonate, with water
  2. customdried
  3. additiontreated with active charcoal
  4. filtrationfiltered
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-7f5d5f55855a44fbaaa4193ca20dedd5
Source dataset
uspto-grants-1989_02
Patent number
US04808210

Reaction notes

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