HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Triphenylphosphoranylidene)acetonitrile → Pyrido(2,3-d)pyrimidine-2,4(1H,3H)-dione, 7-amino-1,3-dimethyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Triphenylphosphoranylidene)acetonitrile | HCID 85524 | — |
| Reactant | 6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidine-5-carbaldehyde | HCID 294688 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | Pyrido(2,3-d)pyrimidine-2,4(1H,3H)-dione, 7-amino-1,3-dimethyl- | HCID 3040482 | 39.5% |
Reaction Steps
0.18 g of 6-amino-5-formyl-1,3-dimethyluracil and 0.45 g of cyanomethylenetriphenylphosphorane were added to 20 ml of dried acetonitrile. The solution was heated under reflux for 12 hr in a stream of argon. After cooling, the precipitated crystal was separated by filtration to give 0.08 g of 7-amino-1,3-dimethylpyrido[2,3-d]pyrimidine-2,4-dione (Compound 15).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808587 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-f26206adcbe9470db5e0e32f33788dcc |
| Source note | uspto-grants-1989_02 |