HCID 14209731, compound → HCID 14209735, compound

Participants

Reaction Steps

A mixture of 188 mg of 10β-(3-bromo-2-propynyl)estr-4-ene-3,17-dione and 376 mg of dichlorodicyanoquinone in 12.5 ml of dioxane is refluxed for 20 hours. The mixture is cooled and diluted with diethyl ether, then washed with aqueous sodium carbonate solution and dried. The solvent is evaporated and the residue is purified by flash chromatography on silica gel eluting with ethyl acetate:n-hexane 30:70 to give the title compound.

Provenance & Evidence