反应详情

A mixture of 5-propyl-1H-imidazole-4-methanol (4.0 g) and manganese (IV) oxide (10.0 g) in 1,4-dioxan (150 ml) was heated at reflux under nitrogen for 1 h. The hot suspension was filtered (Hyflo), washed with hot 1,4-dioxan (100 ml) and evaporated to give the title compound (2.9 g) as a solid, m.p. 120°-124°.

1. temperaturewas heated
2. temperatureat reflux under nitrogen for 1 h
3. filtrationThe hot suspension was filtered (Hyflo)
4. washwashed with hot 1,4-dioxan (100 ml)
5. customevaporated