Ethyl 2-oxocyclohexylacetate → 9-p-Chloro-benzyl-6-isopropyl-1,2,3,4-tetrahydrocarbazol-1-yl-acetic acid

HRID 1382828Notes

Reaction equation

HRID 1382828 reaction equation
Cl.[Cl:2][C:3]1[CH:20]=[CH:19][C:6]([CH2:7][N:8]([C:10]2[CH:15]=[CH:14][C:13]([CH:16]([CH3:18])[CH3:17])=[CH:12][CH:11]=2)N)=[CH:5][CH:4]=1.CC[O:23][C:24]([CH2:26][CH:27]1[C:32](=O)[CH2:31][CH2:30][CH2:29][CH2:28]1)=[O:25]>>[Cl:2][C:3]1[CH:20]=[CH:19][C:6]([CH2:7][N:8]2[C:28]3[CH:27]([CH2:26][C:24]([OH:25])=[O:23])[CH2:32][CH2:31][CH2:30][C:29]=3[C:15]3[C:10]2=[CH:11][CH:12]=[C:13]([CH:16]([CH3:18])[CH3:17])[CH:14]=3)=[CH:5][CH:4]=1

Participants

3

Reactant 2

HCID 91229Ethyl 2-oxocyclohexylacetateHCID 197523941-(4-Chlorobenzyl)-1-[4-(isopropyl)phenyl]hydrazine, Hydrochloride

Product 1

HCID 151575399-p-Chloro-benzyl-6-isopropyl-1,2,3,4-tetrahydrocarbazol-1-yl-acetic acid

Procedure

Following the procedure of Example 1, but using 1(4-chlorobenzyl)-1-(4-isopropylphenyl)hydrazine hydrochloride and ethyl 2-cyclohexanone acetate as starting material, the title compound was prepared.

Sources & evidence

ORD record
ord-9d3878e0fd7940eea6f747d8983f6ea6
Source dataset
uspto-grants-1989_02
Patent number
US04808608

Reaction notes

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