HCID 14300256, compound → HCID 14300252, compound

HRID 1382871Notes

Reaction equation

HRID 1382871 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[C:12]([Cl:13])=[CH:11][C:10]([C:14]([F:17])([F:16])[F:15])=[CH:9][C:8]=2[Cl:18])[N:5]=[C:4]([C:19]([F:22])([F:21])[F:20])[C:3]=1[C:23]([O:25]CC)=[O:24]>S(=O)(=O)(O)O>[NH2:1][C:2]1[N:6]([C:7]2[C:12]([Cl:13])=[CH:11][C:10]([C:14]([F:15])([F:16])[F:17])=[CH:9][C:8]=2[Cl:18])[N:5]=[C:4]([C:19]([F:22])([F:21])[F:20])[C:3]=1[C:23]([OH:25])=[O:24]

Participants

3

Reactant 1

HCID 14300256HCID 14300256, compound

Product 1

HCID 14300252HCID 14300252, compoundYield 86%

Reagents, catalysts & solvents 1

HCID 1118Sulfuric AcidSolvent

Procedure

3.05 G (0.007 mol) of 5-amino-4-ethoxycarbonyl-3-trifluoromethyl-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole in 14 ml of concentrated sulphuric acid are heated at 75° C. for 5 hours. After the mixture has been cooled to room temperature, it is diluted with ice-water and filtered with suction. 2.45 g (86% of theory) of 5-amino-4-hydroxycarbonyl-3-trifluoromethyl-1-(2,6-dichloro-4-trifluoromethylphenyl)pyrazole of melting point 191° C.-195° C. (decomposition) are obtained.

Workup

  1. filtrationfiltered with suction

Sources & evidence

ORD record
ord-b1cc4b5cf5d9435a8607437481d19758
Source dataset
uspto-grants-1989_02
Patent number
US04808623

Reaction notes

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