Ethanol, 1-ethoxy-2,2,2-trifluoro- → 1-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-2-(2,2,2-trifluoroethylidene)hydrazine

HRID 1382872Notes

Reaction equation

HRID 1382872 reaction equation
C(O[CH:4](O)[C:5]([F:8])([F:7])[F:6])C.[Cl:10][C:11]1[CH:16]=[C:15]([C:17]([F:20])([F:19])[F:18])[CH:14]=[C:13]([Cl:21])[C:12]=1[NH:22][NH2:23]>>[Cl:10][C:11]1[CH:16]=[C:15]([C:17]([F:19])([F:18])[F:20])[CH:14]=[C:13]([Cl:21])[C:12]=1[NH:22][N:23]=[CH:4][C:5]([F:6])([F:7])[F:8]

Participants

3

Reactant 2

HCID 9897Ethanol, 1-ethoxy-2,2,2-trifluoro-HCID 688223[2,6-Dichloro-4-(trifluoromethyl)phenyl]hydrazine

Product 1

HCID 534051311-[2,6-Dichloro-4-(trifluoromethyl)phenyl]-2-(2,2,2-trifluoroethylidene)hydrazineYield 89.2%

Conditions

Temperature
100 °C

Procedure

A mixture of 100 g (0.69 mol) of trifluoroacetaldehyde ethyl-hemiacetal and 169.1 g (0.69 mol) of 2,6-dichloro-4-trifluoromethylphenyl hydrazine is heated at 100° C. for 6 hours. After the volatile components have been removed, the residue is recrystallized from petroleum ether. 200 g (89%) of trifluoroacetaldehyde N-(2,6-dichloro-4-trifluoromethylphenyl)-hydrazone of melting point 45° C. to 46° C. are isolated.

Workup

  1. customAfter the volatile components have been removed
  2. customthe residue is recrystallized from petroleum ether

Sources & evidence

ORD record
ord-fdcd7d140a874c20af9f9d812c4e943c
Source dataset
uspto-grants-1989_02
Patent number
US04808623

Reaction notes

Loading…