Methylhydrazine → Phenol, 2,6-bis(1,1-dimethylethyl)-4-(1-methyl-1H-pyrazolo(3,4-b)pyridin-3-yl)-

Participants

Reaction Steps

A mixture of 30 g of 4-(2-chloronicotinoyl)-2,6-di-tertiary butylphenol, 15 g of methylhydrazine and 150 ml of pyridine is reacted and treated in a similar manner as Example 1, and the obtained crude crystals are recrystallized from ethanol to give 27.3 g of 3-(3,5-di-tertiary butyl-4-hydroxyphenyl)-1-methyl-1H-pyrazolo[3,4-b]pyridine as white crystals, melting at 152°-154° C.

Provenance & Evidence