Methylhydrazine → HCID 136139976, compound

HRID 1382882Notes

Reaction equation

HRID 1382882 reaction equation
Cl[C:2]1[N:24]=[C:23]([CH3:25])[CH:22]=[CH:21][C:3]=1[C:4]([C:6]1[CH:11]=[C:10]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:9]([OH:16])=[C:8]([C:17]([CH3:20])([CH3:19])[CH3:18])[CH:7]=1)=O.[CH3:26][NH:27][NH2:28]>>[C:12]([C:10]1[CH:11]=[C:6]([C:4]2[C:3]3[C:2](=[N:24][C:23]([CH3:25])=[CH:22][CH:21]=3)[N:27]([CH3:26])[N:28]=2)[CH:7]=[C:8]([C:17]([CH3:20])([CH3:19])[CH3:18])[C:9]=1[OH:16])([CH3:13])([CH3:15])[CH3:14]

Participants

3

Reactant 2

HCID 6061MethylhydrazineHCID 14368273HCID 14368273, compound

Product 1

HCID 136139976HCID 136139976, compoundYield 91%

Procedure

A mixture of 1.8 g of 4-(2-chloro-6-methylnicotinoyl)-2,6-di-tertiary butylphenol and 0.7 g of methylhydrazine is reacted in a similar manner as Example 1 and the resulting product is recrystallized from ethanol to give 1.6 g of 3-(3,5-di-tertiary butyl-4-hydroxyphenvl)-1,6-dimethyl-1H-pyrazolo[3,4-b]pyridine as white crystals, melting at 178°-181° C.

Workup

  1. customis reacted in a similar manner as Example 1
  2. customthe resulting product is recrystallized from ethanol

Sources & evidence

ORD record
ord-ec4085a26d304af2ac3ccfb9fd834c12
Source dataset
uspto-grants-1989_02
Patent number
US04808620

Reaction notes

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