HCID 21273650, compound → HCID 136456174, compound

HRID 1382899Notes

Reaction equation

HRID 1382899 reaction equation
[C:1]([C:5]1[CH:6]=[C:7]([C:16]2[C:24]3[C:19](=[N:20][CH:21]=[CH:22][CH:23]=3)[NH:18][N:17]=2)[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])([CH3:3])[CH3:2].Cl[CH:26]1[CH2:31][O:30][C:29](=[O:32])[O:28][CH2:27]1>>[C:1]([C:5]1[CH:6]=[C:7]([C:16]2[C:24]3[C:19](=[N:20][CH:21]=[CH:22][CH:23]=3)[N:18]([CH:26]3[CH2:31][O:30][C:29](=[O:32])[O:28][CH2:27]3)[N:17]=2)[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:2])([CH3:3])[CH3:4]

Participants

3

Reactant 2

HCID 21273650HCID 21273650, compoundHCID 178440702HCID 178440702, compound

Product 1

HCID 136456174HCID 136456174, compound

Procedure

By using 3.2 g of the compound of Example 1 and 1.6 g of 5-chloro-2-oxo-1,3-dioxane, the reaction is carried out in a similar manner as Example 78 (i) to give 3-(3,5-di-tertiary butyl-4-hydroxyphenyl)-1-(2-oxo-1,3-dioxan-5-yl)-1H-pyrazolo-[3,4-b]pyridine.

Sources & evidence

ORD record
ord-aee9cc84d82b41e995ac7dfa7b2930c4
Source dataset
uspto-grants-1989_02
Patent number
US04808620

Reaction notes

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