HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isovaleryl chloride → N-(6-(2,4-dichlorophenyl)-5-(4-chlorophenyl)-3-cyanopyridin-2-yl)-N,3-dimethylbutanamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isovaleryl chloride | HCID 66054 | — |
| Reactant | 6-(2,4-Dichlorophenyl)-5-(4-chlorophenyl)-2-(methylamino)pyridine-3-carbonitrile | HCID 68719045 | — |
| Reactant | HCID 178418689 | HCID 178418689 | — |
| Product | N-(6-(2,4-dichlorophenyl)-5-(4-chlorophenyl)-3-cyanopyridin-2-yl)-N,3-dimethylbutanamide | HCID 68717246 | — |
Reaction Steps
The product of Step D Example 1 was reacted with MeMgBr followed by 3-methylbutanoyl chloride using the procedure of EXAMPLE 42 Step A to afford the title compound. HPLC/MS: 472.2 (M+1), 474.2 (M+3); Rt=4.43 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728141B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-f77414101d6f4d47b45db786e34fd591 |
| Source note | uspto-grants-2010_06 |