HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sulfuric Acid → 4-Amino-5-chloro-2-(cyclohexanon-2-yl)oxy-N-[2-(diethylamino)ethyl]benzamide sulfate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-(2-oxo-cyclohexyloxy)-benzamide | HCID 14116891 | — |
| Solvent | Isopropanol | HCID 3776 | — |
| Product | 4-Amino-5-chloro-2-(cyclohexanon-2-yl)oxy-N-[2-(diethylamino)ethyl]benzamide sulfate | HCID 86742764 | — |
Reaction Steps
The 4-amino-5-chloro-2-(cyclohexanon-2-yl)oxy-N-[2-(diethylamino)ethyl]benzamide (190 mg, 0.5 mmole) was dissolved in 25 ml 2-propanol and treated with 1 ml of 1N sulfuric acid. The solution was concentrated under reduced pressure upon which crystallization occurred to yield the title compound, mp. 175° dec.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808624 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-aaa17b7ae32b42d68f00ff766a75735a |
| Source note | uspto-grants-1989_02 |