HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 4-amino-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-3-isopropyl-1-methyl-1,8-naphthyridin-2(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | N-(6-(2,4-dichlorophenyl)-5-(4-chlorophenyl)-3-cyanopyridin-2-yl)-N,3-dimethylbutanamide | HCID 68717246 | — |
| Product | 4-amino-6-(4-chlorophenyl)-7-(2,4-dichlorophenyl)-3-isopropyl-1-methyl-1,8-naphthyridin-2(1H)-one | HCID 11476999 | — |
Reaction Steps
Using the procedure described in EXAMPLE 40, the product of Step A was reacted with NaH to afford the title compound. HPLC/MS: 472.2 (M+1), 474.2 (M+3); Rt=4.45 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728141B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-896a4d1cff104155b2f1ce6c4c277b5b |
| Source note | uspto-grants-2010_06 |