HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenanthrene-9-carbaldehyde → 2-Ethoxymethyl-2-(((9-phenanthrenyl)methyl)amino)-1,3-propanediol hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenanthrene-9-carbaldehyde | HCID 78437 | — |
| Reactant | 2-Amino-2-ethoxymethyl-1,3-propanediol hydrochloride | HCID 15599336 | — |
| Reactant | (+-)(2R*,3S*)-2-((9-Phenanthrenylmethyl)amino)-2-methyl-1,3-butanediol hydrochloride | HCID 86741971 | — |
| Product | 2-Ethoxymethyl-2-(((9-phenanthrenyl)methyl)amino)-1,3-propanediol hydrochloride | HCID 21273664 | — |
Reaction Steps
Using the reductive amination procedure outlined for 7G, phenanthrene-9-carbaldehyde (Aldrich) and 2-amino-2-ethoxymethyl-1,3-propanediol hydrochloride.1/4H2O (8B) gave 2-ethoxymethyl-2-(((9-phenanthrenyl)methyl)amino)-1,3-propanediol hydrochloride mp 173°-175°, (EtOH/Et2O), (C, H, Cl, N).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808625 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-2d3f18eec6094fc68773a16b800e3f2b |
| Source note | uspto-grants-1989_02 |