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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1383040Generated: October 25, 2026

Phenanthrene-9-carbaldehyde → 3-Methoxy-2-methyl-2-((9-phenanthrenylmethyl)amino)-1-propanol hydrochloride

https://huagongshe.com/reaction/1383040

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPhenanthrene-9-carbaldehydeHCID 78437—
Reactant2-Amino-3-methoxy-2-methylpropan-1-olHCID 13375415—
Reactant(+-)(2R*,3S*)-2-((9-Phenanthrenylmethyl)amino)-2-methyl-1,3-butanediol hydrochlorideHCID 86741971—
Product3-Methoxy-2-methyl-2-((9-phenanthrenylmethyl)amino)-1-propanol hydrochlorideHCID 21273677—

Reaction Steps

Using the reductive amination procedure outlined in 7G, phenanthrene-9-carbaldehyde (Aldrich) and 2-amino-3-methoxy-2-methyl-1-propanol (9C) gave 3-methoxy-2-methyl-2-((9-phenanthrenylmethyl)amino)-1-propanol hydrochloride mp 211°-213° (dec), (EtOH/Et2O), (C, H, Cl, N).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04808625
Source datasetuspto-grants-1989_02
ORD IDord-ea5d76f3f7d4440ba7b723b82f674e32
Source noteuspto-grants-1989_02