HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 5-(Ethanesulfonyl)-1,3-benzothiazol-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | 1-Chloro-4-(ethylsulfonyl)-2-nitrobenzene | HCID 1515859 | — |
| Reactant | Thiourea | HCID 2723790 | — |
| Solvent | Sulfolane | HCID 31347 | — |
| Product | 5-(Ethanesulfonyl)-1,3-benzothiazol-2-amine | HCID 21273982 | 85.3% |
Reaction Conditions
| Temperature | 120 °C |
|---|
Reaction Steps
A suspension of 12.8 g of ethyl 4-chloro-3-nitrophenyl sulphone and 15.2 g of thiourea in 50 ml of sulpholane is heated to 120° C. and this temperature is maintained for 1.5 hours. The mixture is discharged into 600 ml of water, and the solid is filtered off with suction and washed with water. 10.6 g of colourless 2-amino-5-ethanesulphonylbenzothiazole are obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808723 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-e308b529ecba4678aba7c09a10c6a3eb |
| Source note | uspto-grants-1989_02 |