2-Chloroethylamine hydrochloride → 4-(7-Chloro-4-cinnolinylamino)-N-(2-chloroethyl)benzenesulphonamide

HRID 1383072Notes

Reaction equation

HRID 1383072 reaction equation
Cl.[Cl:2][CH2:3][CH2:4][NH2:5].Cl.[Cl:7][C:8]1[CH:17]=[C:16]2[C:11]([C:12]([NH:18][C:19]3[CH:24]=[CH:23][C:22]([S:25](Cl)(=[O:27])=[O:26])=[CH:21][CH:20]=3)=[CH:13][N:14]=[N:15]2)=[CH:10][CH:9]=1>>[Cl:7][C:8]1[CH:17]=[C:16]2[C:11]([C:12]([NH:18][C:19]3[CH:20]=[CH:21][C:22]([S:25]([NH:5][CH2:4][CH2:3][Cl:2])(=[O:26])=[O:27])=[CH:23][CH:24]=3)=[CH:13][N:14]=[N:15]2)=[CH:10][CH:9]=1

Participants

3

Reactant 2

HCID 97937372-Chloroethylamine hydrochlorideHCID 212739564-(7-Chloro-4-cinnolinylamino)benzenesulphonylchloride hydrochloride

Product 1

HCID 212739584-(7-Chloro-4-cinnolinylamino)-N-(2-chloroethyl)benzenesulphonamide

Procedure

This compound is prepared in a similar manner to the procedure of Example 10 using equimolar quantities of 2-chloroethylamine hydrochloride instead of 3-chloropropylamine hydrochloride and 4-(7-chloro-4-cinnolinylamino)benzenesulphonyl chloride hydrochloride instead of 4-(7-chloro-4-quinolinylamino)benzenesulphonyl chloride.

Sources & evidence

ORD record
ord-39dff760c5d1416e9c2d6fa3b8859130
Source dataset
uspto-grants-1989_02
Patent number
US04808715

Reaction notes

Loading…