HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,5-Dibromopentane → HCID 14405946, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,5-Dibromopentane | HCID 8100 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 5,6,7,8-Tetrahydro-1-naphthol | HCID 68258 | — |
| Catalyst | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14405946 | HCID 14405946 | 74.8% |
Reaction Steps
The title compound was prepared according to the procedure of Example 7 using 5,6,7,8-tetrahydronaphthalen-1-ol (8 g, 0.054 mol) in methylene chloride (100 ml), sodium hydroxide (4.32 g. 0.108 mol) in water (100 ml), 1,5-dibromopentane (37 g, 0.19 mol) and tetra-n-butylammonium bisulfate (18.3 g, 0.054 mol). Chromatography of the crude product on silica gel using 20% ethyl acetate/hexane as eluent gave 12 g (69%) of the title compound as an oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808729 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-ad32808b36234545bffe8531d2686cab |
| Source note | uspto-grants-1989_02 |