HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Dibromobutane → 1-(4-Bromobutoxy)-2-propylbenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Dibromobutane | HCID 8056 | — |
| Reactant | 2-Propylphenol | HCID 12570 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Catalyst | Tetrabutylammonium hydrogen sulfate | HCID 94433 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-(4-Bromobutoxy)-2-propylbenzene | HCID 14405948 | 101% |
Reaction Steps
The title compound was prepared according to the procedure of Example 7 using 2-n-propylphenol (10 g, 0.073 mol) in methylene chloride (100 ml), sodium hydroxide (6.0 g, 0.146 mol) in water (100 ml), 1,4-dibromobutane (55 g, 0.255 mol) and tetra-n-butylammonium bisulfate (26 g, 0.073 mol). The crude product was distilled (b.p. 110°-112°/0.25 mm Hg) to give 20 g (80%) of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808729 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-c507ca7079e84e21828ae8f85c8d746f |
| Source note | uspto-grants-1989_02 |