HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimercaprol → HCID 14748488, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimercaprol | HCID 3080 | — |
| Reactant | Boron trifluoride etherate | HCID 8000 | — |
| Reactant | Benzenebutanoic acid, gamma-oxo-, methyl ester | HCID 141190 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 14748488 | HCID 14748488 | — |
Reaction Steps
The title compound was prepared according to the procedure of Example 1 using 2,3-dimercapto-1-propanol (2.3 g, 0.019 mol), methyl 3-benzoylpropionate from Example 67 (3.7 g, 0.019 mol) and boron trifluoride etherate (0.5 ml) in methylene chloride (50 ml). The crude product was chromatographed on silica gel using 1% acetone/toluene as eluent to give 1.0 g (31%) of product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04808729 |
| Source dataset | uspto-grants-1989_02 |
| ORD ID | ord-cec6443d529f4f1abdc85d7d54f92117 |
| Source note | uspto-grants-1989_02 |