HCID 54461430, compound → HCID 21187204, compound

HRID 1383263Notes

Reaction equation

HRID 1383263 reaction equation
[F:1][CH2:2][CH2:3][CH2:4][CH:5]=[CH:6][C:7]1[CH:8]=[C:9]([F:13])[CH:10]=[CH:11][CH:12]=1>[Pd].C(O)C>[F:1][CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][C:7]1[CH:8]=[C:9]([F:13])[CH:10]=[CH:11][CH:12]=1

Participants

4

Reactant 1

HCID 54461430HCID 54461430, compound

Product 1

HCID 21187204HCID 21187204, compoundYield 64.4%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

Then, 5% Pd—C 4 g and ethanol 100 ml were added to 3-(5-fluoro-1-pentenyl) fluorobenzene 86 g (472 mmol) to conduct a reaction of catalytic hydrogenation reduction. After the hydrogen absorption was stopped, the catalyst was filtered off, and the filtrate was distilled(62° C./2 mmHg) to obtain 3-(5-fluoropentyl) fluorobenzene 56 g. (Yield: 64.4%).

Workup

  1. customa reaction of catalytic hydrogenation reduction
  2. customAfter the hydrogen absorption
  3. filtrationthe catalyst was filtered off
  4. distillationthe filtrate was distilled(62° C./2 mmHg)

Sources & evidence

ORD record
ord-d045791df1174ddc9f825cecb3262e4a
Source dataset
uspto-grants-2001_07
Patent number
US06254941B1

Reaction notes

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