10-bromodecanal → HCID 88227136, compound

Participants

Reaction Steps

68.1 g (149 mmol) of (4-carboxy-3-methyl-butyl)-triphenylphosphonium bromide were placed in 150 ml of THF and treated with 33.4 g (298 mmol) of potassium t-butylate in 50 ml of THF. 35 g (149 mmol) of 10-bromodecanal were added to this mixture After usual work up 111.8 g of crude product were obtained and, after chromatography, 29 g of 3-methyl-5Z-15-bromopentadec-5-enoic acid were obtained having the following characteristics:

Provenance & Evidence