反应详情

To a solution 3-methoxy-5-methylphenylacetic acid of (8.1 g; 0.045 mol; from step (iii) above) in EtOH (100 mL) was added H2SO4 (conc.), and the solution was left to stand for 40 hours. The reaction mixture was concentrated, and the crude product was partitioned between water and ether. The organic layer was washed with NaHCO3/aq and water, dried (Na2SO4), and evaporated to yield 8.0 g (85%) of the sub-title compound as a brown oil.

1. waitthe solution was left
2. concentrationThe reaction mixture was concentrated
3. customthe crude product was partitioned between water and ether
4. washThe organic layer was washed with NaHCO3/aq and water
5. dry with materialdried (Na2SO4)
6. customevaporated