Potassium Hydroxide → HCID 21188012, compound

Participants

Reaction Steps

A solution of 8,4 g of 2,3-di(methoxycarbonyl)-1-(2-methoxyphenyl)-4-phenyl-pyrrole and 2.6 g of KOH in diethyleneglycol monomethylether is refluxed for 3 hours. After cooling it is poured onto water, acidified and extracted 3 times with diethylether. The combined organic phases are washed with water, dried and evaporated down. The crude product is crystallised from diethylether. 4,8 g of 2,3-dicarboxy-1-(2-methoxyphenyl)-4-phenyl-pyrrole are obtained.

Provenance & Evidence