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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1383897Generated: October 27, 2026

Benzenepropanoic acid, 4-hydroxy-, methyl ester → 3-[4-[3-(N-dodecyl-N-methylamino)propoxy]phenyl]propanoic acid, methyl ester

https://huagongshe.com/reaction/1383897

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzenepropanoic acid, 4-hydroxy-, methyl esterHCID 79706—
Reactant3-[Dodecyl(methyl)amino]propan-1-OLHCID 13122261—
Product3-[4-[3-(N-dodecyl-N-methylamino)propoxy]phenyl]propanoic acid, methyl esterHCID 8675711568%

Reaction Steps

Methyl 3-(4-hydroxyphenyl)propanoate (1.0 g, 5.5 mmol) and 3-(N-dodecyl-N-methylamino)propanol (1.43 g, 5.5 mmol) were reacted as described in example 1 to give 1.57 g (43%) of title material as an oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06255496B1
Source datasetuspto-grants-2001_07
ORD IDord-3fc1a7c464dc42d1acb7cad40735efe9
Source noteuspto-grants-2001_07