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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1383898Generated: October 25, 2026

2-Trifluoroacetylphenol → [2-[2-(N-Dodecyl-N-methylamino)ethoxy]phenyl]-2,2,2-trifluoroethanone

https://huagongshe.com/reaction/1383898

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-TrifluoroacetylphenolHCID 2761164—
ReactantDodecyl(2-hydroxyethyl)methylamineHCID 10657884—
Product[2-[2-(N-Dodecyl-N-methylamino)ethoxy]phenyl]-2,2,2-trifluoroethanoneHCID 1831914561.2%

Reaction Steps

2-Trifluoroacetylphenol (Matsumoto, S.; Kobayashi, H. and Ueno, K. Bull. Chem. Soc. Jpn. 1969, 42, 960) (490 mg, 2.57 mmol) and 2-[N-dodecyl-N-methylamino] ethanol (627 mg, 2.58 mmol) were reacted by the general procedure as described in example 1 and afforded the title compound (654 mg, 61%) as a pale yellow oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06255496B1
Source datasetuspto-grants-2001_07
ORD IDord-e01239760fc14bd2aada696da08cc869
Source noteuspto-grants-2001_07