Methanol → 3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-hydroxyphenyl]propanoic acid, methyl ester

HRID 1383899Notes

Reaction equation

HRID 1383899 reaction equation
[CH2:1]([N:13]([CH2:15][CH2:16][O:17][C:18]1[CH:28]=[CH:27][C:21]2[CH2:22][CH2:23][C:24](=[O:26])[O:25][C:20]=2[CH:19]=1)[CH3:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[CH3:29][OH:30]>>[CH2:1]([N:13]([CH2:15][CH2:16][O:17][C:18]1[CH:28]=[CH:27][C:21]([CH2:22][CH2:23][C:24]([O:30][CH3:29])=[O:26])=[C:20]([OH:25])[CH:19]=1)[CH3:14])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 887MethanolHCID 18319080HCID 18319080, compound

Product 1

HCID 867571163-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-hydroxyphenyl]propanoic acid, methyl esterYield 100%

Procedure

A solution of 7-[2-(N-Dodecyl-N-methylamino)ethoxy]-3,4-dihydro-2H-1-benzopyran-2-one (2.0 g, 5.13 mmol) in methanol (30 ml) was stirred at 22° C. for 0.5 h. The solvent was then removed in vacuo at 40° C. to afford the title compound (2.14 g, 100%) as a white solid.

Workup

  1. customThe solvent was then removed in vacuo at 40° C.

Sources & evidence

ORD record
ord-2b7609e195f84f4580543faab07573dd
Source dataset
uspto-grants-2001_07
Patent number
US06255496B1

Reaction notes

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