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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1383901Generated: October 31, 2026

3-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]propanoic acid, hydrochloride → 3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, hydrochloride

https://huagongshe.com/reaction/1383901

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]propanoic acid, hydrochlorideHCID 70228655—
Reactant3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, methyl esterHCID 86757117—
Product3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, hydrochlorideHCID 13172275962%

Reaction Steps

3-[4-[2-(N-Dodecyl-N-methylamino)ethoxy]-2-methoxyphenyl]propanoic acid, methyl ester (468 mg, 1.07 mmol) was saponified as described in the preparation of 3-[4-[2-(N-dodecyl-N-methylamino)ethoxy]phenyl]propanoic acid, hydrochloride and afforded the title compound (280 mg, 62%) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06255496B1
Source datasetuspto-grants-2001_07
ORD IDord-12fa396ed6ab4b3994bdb5811c3548b2
Source noteuspto-grants-2001_07