HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Chloroaniline → 7-Acetamino-1-(3-chloroanilino)-4-(4-pyridylmethyl)phthalazine hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Chloroaniline | HCID 7932 | — |
| Reactant | 7-Acetamino-1-chloro-4-(4-pyridylmethyl)phthalazine | HCID 22741951 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 7-Acetamino-1-(3-chloroanilino)-4-(4-pyridylmethyl)phthalazine hydrochloride | HCID 22742013 | — |
Reaction Steps
By analogy with Example 25, 300 mg (0.96 mmol) 7-acetamino-1-chloro-4-(4-pyridylmethyl)-phthalazine is reacted in 3.9 ml 1-butanol with 302 μl (2.88 mmol) 3-chloroaniline. Suspension of the raw product in 1 ml boiling ethanol and filtration lead to the title compound: HPLC: tRet(Grad5-40)=11.3; FAB MS (M+H)+=404.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06258812B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-09a47602b80a495193e49eb1c8bcc24f |
| Source note | uspto-grants-2001_07 |