Tributylamine → HCID 21185896, compound

Participants

Reaction Steps

A solution of 6-[1-(2-iodophenyl)vinyl]-1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene (9.5 g, 22 mmol), palladium diacetate (560 mg, 2.5 mmol)-and tributylamine (12 ml, 50 mmol) in methanol (500 ml) is heated for 3 h at 100° C. under a pressure of carbon monoxide (3 bar). After concentration on an evaporator under vacuum at 40° C., the oil obtained is diluted in ethyl acetate and washed three times with water. The product is purified by flash chromatography on a column of silica.

Provenance & Evidence