Tributylamine → HCID 86757135, compound

Participants

Reaction Steps

A solution of (3-iodophenyl)-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)methanone oxime (320 mg, 0.7 mmol), palladium diacetate (20 mg, 89 μmol), tributylamine (392 μl, 1.7 mmol) and ethyl acrylate (78 μl, 0.7 mmol) in acetonitrile (10 ml) is heated for 4 h at 80° C. The reaction medium is extracted with ethyl ether and washed with water. After drying, the organic phase is concentrated on a rotary evaporator under vacuum at 40° C. The product is purified by flash- chromatography on a column of silica.

Provenance & Evidence