反应详情

A suspension of Example 8C (31 g, 135 mmole) in trimethyl phosphate (450 mL) was treated with triphosgenie (27 g, 136 mmole), stirred for 20 min at room temperature and heated in an oil bath at 80° C. for 1 h. The product precipated from the solution while cooling to room temperature. The thick slutty was treated with water and filtered, and the white solid was thoroughly washed with water and dried under vacuum to provide 26.3 g of the title compound.

1. temperatureheated in an oil bath at 80° C. for 1 h
2. temperaturewhile cooling to room temperature
3. filtrationfiltered
4. washthe white solid was thoroughly washed with water
5. customdried under vacuum