Sodium borohydride → HCID 15857587, compound

Participants

Reaction Steps

the aldehyde (19) (0.303 gm., 1 mmol) was dissolved in absolute ethanol (5 mL) and sodium borohydride (0.05 gm., 1 mmol) was added at room temperature. After stirring for 30 min. the mixture was poured into 10 mL brine and extracted with CH2Cl2 (3×10 mL). The extracts were dried over MgSO4 and evaporated to dryness to yield the desired alcohol (20) (0.264 gm., 0.86 mmol, 86%).

Provenance & Evidence