Hydrogen Bromide → HCID 15857588, compound

Participants

Reaction Steps

the alcohol (20) (0.200 gm., 0.65 mmol) was dissolved in 5 mL HBr (45%) and refluxed for 6 hours. After cooling to room temperature the mixture was poured over 20 gm. of crushed ice, basified with saturated aqueous solution of Na2CO3 and extracted with CH2Cl2. The extracts were dried over (MgSO4) and evaporated to dryness to yield the bromo derivative (21) (0.186 gm., 0.51 mmol, 78%).

Provenance & Evidence