HuagongsheHuagongshe Chemistry Print Report · For research reference only
Pyridine → Methyl 4-bromo-3-oxooctadecanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 2,2-Dimethyl-1,3-dioxane-4,6-dione | HCID 16249 | — |
| Reactant | 2-Bromohexadecanoyl chloride | HCID 11131956 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Product | Methyl 4-bromo-3-oxooctadecanoate | HCID 21187102 | — |
Reaction Steps
1.8 mol of Meldrum's acid were mixed with 3.96 mol of pyridine in a round-bottomed flask containing 1,2-dichloroethane, placed at 0° C. under argon and with stirring. 1.98 mol of 2-bromohexadecanoyl chloride were then introduced slowly and the mixture was left stirring for 2 hours at 0° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06258977B1 |
| Source dataset | uspto-grants-2001_07 |
| ORD ID | ord-b0f50c532c124e609ad86ec4c8489a05 |
| Source note | uspto-grants-2001_07 |