反应详情

(R)-2-acetoxy-4-oxo-4-phenylbutyric acid (2.36 g) was dissolved in 15 ml of acetic acid, and 0.21 g of 5% by weight palladium on carbon (water content 50%) were added thereto. The mixture was stirred in a hydrogen atmosphere at 60° C. for 24 hours. Palladium on carbon was separated by filtration, and the solvent was then distilled off. Thirty milliliters of 1−N hydrochloric acid were added to the resulting (R)-2-acetoxy-4-phenylbutyric acid, and the mixture was heat-refluxed for 3 hours while being stirred.

1. customPalladium on carbon was separated by filtration
2. distillationthe solvent was then distilled off
3. additionThirty milliliters of 1−N hydrochloric acid were added to the resulting (R)-2-acetoxy-4-phenylbutyric acid
4. temperaturethe mixture was heat-refluxed for 3 hours