HRID1384695

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)O)C(C)C

HCID22875497

未命名化合物

结构：C=CCOC(=O)N1CC(OCc2ccccc2)C[C@H]1C(=O)NC(C=O)CC(=NNC(N)=O)OC(C)(C)C

HCID53707120

未命名化合物

PRODUCTS

生成物

结构：CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@H](C(=O)N1CC(OCc2ccccc2)C[C@H]1C(=O)NC(C=O)CC(=NNC(N)=O)OC(C)(C)C)C(C)C

HCID53915659

未命名化合物

PROCEDURE

实验过程

The title compound was prepared by reaction of N-acetyl-tyrosinyl-valine and N-(N-allyloxycarbonyl-4-benzyloxyprolinyl)-3-amino-4-oxobutanoic acid tert-butyl ester semicarbazone by reaction conditions reported for compound H, step A.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-e187a326e5464d13b0d8d07a2d175199
来源数据集: uspto-grants-2001_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06258948B1
来源说明: uspto-grants-2001_07

反应 SMILES

[C:1]([NH:4][C@H:5]([C:14]([NH:16][C@H:17]([C:21]([OH:23])=O)[CH:18]([CH3:20])[CH3:19])=[O:15])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([OH:13])=[CH:9][CH:8]=1)(=[O:3])[CH3:2].[C:24]([O:28][C:29](=[N:56][NH:57][C:58]([NH2:60])=[O:59])[CH2:30][CH:31]([NH:34][C:35](=[O:55])[C@@H:36]1[CH2:40][CH:39]([O:41][CH2:42][C:43]2[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=2)[CH2:38][N:37]1C(OCC=C)=O)[CH:32]=[O:33])([CH3:27])([CH3:26])[CH3:25]>>[C:24]([O:28][C:29](=[N:56][NH:57][C:58]([NH2:60])=[O:59])[CH2:30][CH:31]([NH:34][C:35](=[O:55])[C@@H:36]1[CH2:40][CH:39]([O:41][CH2:42][C:43]2[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=2)[CH2:38][N:37]1[C:21](=[O:23])[C@H:17]([CH:18]([CH3:19])[CH3:20])[NH:16][C:14](=[O:15])[C@H:5]([CH2:6][C:7]1[CH:8]=[CH:9][C:10]([OH:13])=[CH:11][CH:12]=1)[NH:4][C:1](=[O:3])[CH3:2])[CH:32]=[O:33])([CH3:27])([CH3:25])[CH3:26]